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Bush Doctrine: The Pharmaceutical Safety Data Problem
Explore Bio-IT World (Jan 27 2012)
Bio-IT World | The Bush Doctrine: What the industry calls “safety data” covers everything from discovery-oriented in vitro or cell based studies to extensive GLP toxicology study data, voluminous clinical study records, and post-marketing/pharmacovigilance systems. It leads one to wonder: does anyone have informatics systems that allow safety investigators across the pharma enterprise to effectively mine this ocean of information?
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Accelrys Launches Next-Generation Informatics Suite and Cloud Portal
Explore Bio-IT World (Oct 12 2011)
Bio-IT World | Accelrys is releasing its "next-generation informatics suite" this week, including a chemical registration system and a Cloud-based portal called HEOS in partnership with SCYNEXIS, in what one company executive calls the first coherent suite to span scientists' daily workflows since the 2010 merger with Symyx. (Read Full Article)
Carole Goble: Democratizing Informatics for the ‘Long Tail’ Scientist
Explore Bio-IT World (Mar 31 2011)
March 31, 2011 | In 1979, Carole Goble went to the University of Manchester to study computer science, and never looked back. She has helped create and/or develop a host of life science tools including Taverna, myExperiment, and BioCatalogue, all in the name of democratizing informatics. Goble recently spoke to Bio•IT World editor-in-chief Kevin Davies about her mission to democratize informatics for life sciences.
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FDA Works to Become More Transparent
Explore Bio-IT World (Mar 29 2011)
By John Russell March 29, 2011 | The Russell Transcript | How many genomic data sets were submitted to FDA under the VXDS (voluntary exploratory data submissions) program last year? Is the agency meeting its hiring goals? How many manufacturing
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The Psychology of ‘Smarter’ Drug Discovery
Explore Bio-IT World (Mar 29 2011)
Researchers identify four cognitive biases that might be slowing drug discovery. By Courtney Andersen March 29, 2011 | In an age of increasing financial and logistical pressures facing biotech and pharmaceutical companies, optimizing R&D success is a critical task. But (Read Full Article)
Growth Coming for Molecular Diagnostics
Explore Bio-IT World (Mar 29 2011)
By Al Doig March 29, 2011 | Insights Outlook | Molecular diagnostics (MDx), a branch of in vitro diagnostics, is based on determining nucleic acid sequences mainly for medical applications. Sequence determination is largely performed using methods based on hybridization
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GenoLogics Eyes Next-Gen LIMS Market
Explore Bio-IT World (Mar 29 2011)
A recent partnership with Illumina is taking the company to ‘another level.’ By Kevin Davies March 29, 2011 | Michael Ball, CEO of GenoLogics, thinks that Illumina’s recent partnership with his company to sell GenoLogics’ LIMS (Laboratory Information Management System)
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Banking on Biosimilars
Explore Bio-IT World (Jan 14 2011)
Reuters | Several announcements recently have illustrated that drugmakers are seeing money in generics. Merck just struck a deal with Parexel to create biosimilars.
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2011 Bio-IT World Best Practices Open
Explore Bio-IT World (Oct 18 2010)
Bio-IT World | The 2011 Bio-IT World Best Practices competition has released its call for entries. Since 2003, Bio-IT World's Best Practices competition has been recognizing outstanding examples of technology and strategic innovation initiatives across the drug discovery enterprise. The deadline for entry is January 14, 2011, and the early bird deadline is December 19, 2010.
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Integrating InForm EDC at Dana-Farber Cancer Institute
Explore Bio-IT World (Sep 22 2010)
Bio-IT World | The Dana-Farber/Harvard Cancer Center, the largest cancer center in the United States, runs about 800 cancer clinical trials per year. And yet until 2000, all of those trials were tracked on paper, and researchers were still grappling with data gaps common to paper records. (Read Full Article)
May-June Contents
Explore Bio-IT World (Jul 1 2010)
Feature A Social Approach to Patient Recruitment Better use of Web 2.0 sites like Twitter, Facebook and PatientsLikeMe could be a boon for enrollment. Special Report Bio IT World Conference & Expo 2010 Four Secrets to Success Christoph Westphal dishes
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invivodata: FDA’s New PRO Guidance Highlights Patient’s Perspective
Explore Bio-IT World (May 18 2010)
eCliniqua | Evidence is mounting that the Food and Drug Administration (FDA) wants to hear the voice of the patient in clinical trials. "They want to make sure PRO data are collected in a reliable way so they can make reasonable judgments based on those data,” says Doug Engfer, president and CEO of invivodata.
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No KIDding: Informatics in Reverse
Explore Bio-IT World (May 14 2010)
Bio-IT World | “We’re not working on bioinformatics, we’re creating chaos!," says Parthiban Srinivasan, founder of Parthys Reverse Informatics, based in Chennai, India. "Everybody’s worried about having too much data, but we’re delivering data from existing knowledge. So informatics goes from data to information to knowledge. We [Parthys] go from knowledge to information to data. It’s reverse informatics.”
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Accelrys Announces Pipeline Pilot 8.0 Scientific Informatics Platform
Explore Bio-IT World (May 5 2010)
April 5, 2010 | Accelrys, the San Diego-based informatics software and services company, has announced the latest release of its leading scientific informatics platform, Accelrys Pipeline Pilot 8.0. The new edition of the workflow software, which was previewed last month at Bio-IT World Expo, aims to support more researchers working individually or as teams across the scientific R&D enterprise.
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Accelrys, Symyx Technologies Announce Informatics Merger
Explore Bio-IT World (Apr 5 2010)
Bio-IT World | Accelrys and Symyx Technologies have announced that the two informatics companies will merge in an all-stock deal expected to close by June 2010. The name of the new company has not yet been announced.
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Comment Mentions: Symyx Technologies
Thermo’s Bold Bet on LIMS-on-Demand
Explore Bio-IT World (Mar 25 2010)
Bio-IT World | For several years the LIMS market (roughly $400M worldwide) has been stuck in neutral. Indeed, depending upon whose estimate you believe, perhaps 80 percent of labs forego the use of commercial LIMS for a variety of well-documented reasons – high cost, year-long deployment efforts, inflexibility, etc. That’s all about to change, says Kim Shah, ThermoFisher Scientific’s director of marketing, informatics, and Thermo will lead the charge. (Read Full Article)
Amazon’s Deepak Singh to Give Cloud Computing Keynote at Bio-IT World Expo
Explore Bio-IT World (Mar 8 2010)
Bio-IT World | Deepak Singh, business development manager at Amazon Web Services, has been named as the third and final keynote speaker at the 2010 Bio-IT World Expo, where he will be presenting on cloud computing for life sciences.
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U.S. Scientists Given Access to Cloud Computing by Microsoft
Explore Bio-IT World (Feb 5 2010)
New York Times | Microsoft and the National Science Foundation have agreed to offer American scientific researchers free access to the company’s new cloud computing service. A goal of the three-year project is to give scientists the computing power to cope with exploding amounts of research data.
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Bill Gates Pledges $10 Billion for 'Decade of Vaccine'
Explore Bio-IT World (Jan 29 2010)
The Times | At the World Economic Forum in Davos, Switzerland, Bill Gates announced the largest ever single charitable donation -- $10 billion over ten years -- which he hoped would mark the “decade of the vaccine,” saving 8 million lives.
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Drug Discovery Database Goes Live with 2.4 Million Records
Explore Bio-IT World (Jan 21 2010)
Bio-IT World | ChEMBLdb, a vast open-source database of the properties and activities of drugs and drug-like small molecules and their targets, launched this week with information on over half a million compounds.
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Drug Discovery in Dundee: A Q&a with Andrew Hopkins
Explore Bio-IT World (Jan 21 2010)
Bio-IT World | While working at Pfizer in the U.K. some 9 years ago, Andrew Hopkins and his colleague Colin Groom coined the phrase “the druggable genome”—a systematic analysis of the number of druggable targets in the human genome. In 2007, Hopkins made the bold decision to quit industry for academia. Hopkins says it’s taken a good two years to adapt from industry, but things are finally starting to come together. With patents filed, compounds being synthesized, biophysics and informatics operations up and running, Hopkins granted Bio•IT World this exclusive interview.
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Warm Wellcome for Cloud Computing
Explore Bio-IT World (Dec 7 2009)
Bio-IT World | With a sequencing output approaching 500 Gigabases/week and electricity consumption a whopping 3 MegaWatts, the Wellcome Trust Sanger Institute (WTSI) is a prime contender for cloud computing. Guy Coates, group leader of informatics systems at WTSI, heads a quasi internal consulting team that sits between the hardcore systems teams and the research scientists. Kevin Davies caught up with Coates at Bio-IT World Europe to discuss the institute’s early experiences with cloud computing.
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Pharma's Early Cloud Adopters
Explore Bio-IT World (Nov 25 2009)
Bio-IT World | Andrew Kaczorek, associate information consultant with Eli Lilly, has been experimenting with Amazon Web Services (AWS). “The amount of time it spends and the amount of dollars it costs are entirely predictable. If [researchers] know exactly what workload that they’re pushing into it, they can know exactly when it should be done and how much their bill is going to be.” (Read Full Article)
Telomere Researchers Share Nobel Prize for Medicine
Explore Bio-IT World (Oct 8 2009)
New York Times | American molecular biologists Elizabeth Blackburn, Carol Grieder, and Jack Szostak have shared the 2009 Nobel Prize for Physiology or Medicine for their research on telomeres, the aglets of chromosomes. (Read Full Article)
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